-- women have about 10 times less testosterone than do men*.So as you can see, with a sex change operation the underlying DNA stays whatever sex they started out with.As you know, testosterone is the "male hormone." However, testosterone by itself can do nothing -- it needs a protein called the androgen receptor to have any effect.Like testosterone, the androgen receptor by itself can't do anything either.
In the womb, these genes cause male plumbing to develop.Our findings reveal that the hypothalamic–pituitary–gonadal axis drives Mib1 expression in the myofibre niche. Moreover, the same axis regulates the re-establishment of quiescent satellite cell populations following injury. In fact the gene for the androgen receptor is found on the X chromosome.Why would women have any androgen receptors lying around?